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Glam Journal

Is Encephalomalacia the same as PVL?

Author

Elijah King

Updated on March 02, 2026

Is Encephalomalacia the same as PVL?

PVL is seldom associated with mass effect and displacement of surrounding structures. Cystic encephalomalacia appears in the areas of increased echogenicity within 2 to 3 weeks after the initial insult (Figure 59-25). These are characterized by cysts ranging between 1 mm and 2-3 cm in size.

What is periventricular Encephalomalacia?

Periventricular leukomalacia (PVL) is a softening of white brain tissue near the ventricles. The ventricles are fluid-filled chambers in the brain. These are the spaces in the brain that contain the cerebrospinal fluid (CSF).

What causes periventricular leukomalacia?

Although the exact cause of PVL is not known, the condition is thought to be caused when the areas of the brain around the ventricles (the fluid-filled spaces of the brain) don’t get enough blood. This area of the brain is very prone to injury, especially in premature babies whose brain tissue is fragile.

Is periventricular leukomalacia neurological disorder?

Periventricular leukomalacia (PVL) is a common neurological morbidity in preterm infants, and it is one of the most common causes of cerebral palsy in these infants.

How is periventricular leukomalacia diagnosis?

How is periventricular leukomalacia diagnosed? In addition to a complete medical history and physical examination, diagnostic procedures for PVL may include: Cranial ultrasound. A painless test that uses sound waves to view the baby’s brain through the fontanelles, the soft openings between the skull bones.

Is periventricular leukomalacia a disability?

Most premature babies diagnosed with PVL will go on to have some form of disability, however mild cases of PVL may have no lasting disability.

How many people have periventricular leukomalacia?

It is estimated that approximately 3-4% of infants who weigh less than 1,500 g (3.3 lb) have PVL, and 4-10% of those born prior to 33 weeks of gestation (but who survive more than three days postpartum) have the disorder.

How do you prevent periventricular leukomalacia?

Following delivery of a premature infant, attempts to minimize blood pressure (BP) swings and hypotension may also be beneficial in preventing periventricular leukomalacia. Avoidance of prolonged hypocarbia in the mechanically ventilated premature infant may be useful in the prevention of periventricular leukomalacia.

What does periventricular white matter mean?

Those around the center black spaces are called “periventricular white matter lesions”. Those located between the cortex and ventricles, with some space between, are just called “white matter lesions”.

Can white matter repair itself?

White matter injuries are very serious, but, depending on the type and extent of the injury, extensive recovery may occur. As long as the neuron cell bodies remain healthy, axons can regrow and slowly repair themselves.

Can PVL cause seizures?

Children with PVL may have seizures. A study in Israel of 541 patients showed that 18.7% of those experienced seizures. Seizures are more common in those born prematurely and with low birth weight.

How many years can you live with white matter disease?

It is not possible to stop disease progression, and it is typically fatal within 6 months to 4 years of symptom onset. People with the juvenile form of metachromatic leukodystrophy, which develops between the age of 4 and adolescence, may live for many years after diagnosis.